A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer

(Cell Metabolism 30, 1107–1119.e1–e8; December 3, 2019) As a result of an author oversight in the originally published version this article, example image H&E staining for HKB99 group was accidentally sourced from lung section mice harboring HCC827-Luc, instead HCC827ER9-Luc, when Figure 6F assembled. This error does not affect any results or conclusions paper. The authors sincerely apologize confusion and inconvenience that may have caused. A Novel Allosteric Inhibitor Phosphoglycerate Mutase 1 Suppresses Growth Metastasis Non-Small-Cell Lung CancerHuang et al.Cell MetabolismOctober 10, 2019In BriefPGAM1 plays critical role cancer cell metabolism. Huang al. discovered novel PGAM1 inhibitor HKB99, which allosterically blocks structure PGAM1, impacting both its catalytic activity ACTA2 interaction. significantly inhibits NSCLC tumor growth metastasis vivo by PGAM1’s metabolic nonmetabolic function. Full-Text PDF Open Archive